Feeling Pretty Doomed

You know that feeling like you have a bad feeling something is about to happen? I think we all know that feeling. That's how I feel about my marriage and life. I married a high-school friend after reuniting in college. I got a 4-year degree, got that first job, was laid off, went back to school, got a useless masters degree, and now as I work I'm going back to school to change careers into something more reliable and that I can do into old age because I'll never retire. My issues are that I still barely make ends meet. Financial strain, the costs of fertility treatment, the obliterated intimacy in my marriage, the fact that I have MDD, the fact that I don't find my wife attractive anymore, these are all starting to look like a recipe for disaster. I know that sometimes "when you're going through hell, keep on going" but the road is on fire, the car is on fire, I'm on fire, everything is on fire and I'm just looking around wondering if I'm driving in the right direction. I'm not brilliant but I'm not too stupid and stubborn to ask for directions. Does anyone have some directions?